Ultrasonically triggered drug delivery: Breaking the barrier
نویسندگان
چکیده
منابع مشابه
Breaking the therapeutic drug monitoring logistics barrier.
Therapeutic drug monitoring (TDM) is one of the most complex laboratory testing processes in modern laboratory medicine practice. Based on the simple engineering principle of feedback control, TDM strives to regulate an individual’s exposure to a drug by measuring the drug’s concentrations, usually at steady state and at distributional equilibrium, and then use these concentrations to determine...
متن کاملMechanical Force-Triggered Drug Delivery.
Advanced drug delivery systems (DDS) enhance treatment efficacy of different therapeutics in a dosage, spatial, and/or temporal controlled manner. To date, numerous chemical- or physical-based stimuli-responsive formulations or devices for controlled drug release have been developed. Among them, the emerging mechanical force-based stimulus offers a convenient and robust controlled drug release ...
متن کاملMechanistic Studies of Ultrasonically-Enhanced Transdermal Drug Delivery
Transdermal drug delivery (TDD), a painless, non-invasive method of drug delivery, is limited to only a handful of drugs due to the low permeability of skin, The application of low frequency ultrasound significantly enhances transdemal transpor[ of a variety of drugs (sonophoresis), most likely through cavitation-related phenomena. It is unclear whether the primary effect of ultrasound is on th...
متن کاملUltrasonically activated chemotherapeutic drug delivery in a rat model.
Systemic delivery of anticancer agents is accompanied by many unwanted side effects that can be mitigated by encapsulation of antineoplastic agents. However, encapsulation necessitates a technique for controlled delivery to the cancerous tissue. We have developed a novel drug delivery system that releases drug from stabilized micelles upon application of low-frequency ultrasound and that demons...
متن کاملPolymeric nanoparticles for hypoxia-triggered drug delivery
864 ©2014 Society for Biomaterials
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Colloids and Surfaces B: Biointerfaces
سال: 2014
ISSN: 0927-7765
DOI: 10.1016/j.colsurfb.2014.07.051